Indian Journal of Health Sciences and Biomedical Research KLEU

MINI REVIEW ARTICLE
Year
: 2021  |  Volume : 14  |  Issue : 1  |  Page : 22--30

Prostate-Specific antigen: An overview and its current status in the diagnosis of prostate cancer


Siddalingeshwar Neeli, Manas Sharma, Abhijit Musale 
 Department of Urology, KLE Academy of Higher Education and Research (Deemed-to-be-University), Belagavi, Karnataka, India

Correspondence Address:
Dr. Siddalingeshwar Neeli
Department of Urology, KLE Academy of Higher Education and Research (Deemed-to-be-University), JNMC Campus, Belagavi - 590 010, Karnataka
India

Prostate-Specific Antigen (PSA), which has high organ specificity and poor cancer specificity, has been widely utilized for the diagnosis and treatment of prostate cancer; though it is not an ideal tumor marker. Its extensive usage in screening programs has resulted in a large number of unwanted biopsies, over-diagnosis and over-treatment of indolent cancers as well. Hence, various PSA derivatives and PSA-based tests have evolved to improve the accuracy of prostate cancer diagnosis. This article provides an overview of PSA and PSA-based biomarkers and their current role in the screening and diagnosis of prostate cancer.


How to cite this article:
Neeli S, Sharma M, Musale A. Prostate-Specific antigen: An overview and its current status in the diagnosis of prostate cancer.Indian J Health Sci Biomed Res 2021;14:22-30


How to cite this URL:
Neeli S, Sharma M, Musale A. Prostate-Specific antigen: An overview and its current status in the diagnosis of prostate cancer. Indian J Health Sci Biomed Res [serial online] 2021 [cited 2021 Apr 23 ];14:22-30
Available from: https://www.ijournalhs.org/article.asp?issn=2542-6214;year=2021;volume=14;issue=1;spage=22;epage=30;aulast=Neeli;type=0