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  Indian J Med Microbiol
 

Figure 2: Normally, the prefrontal cortex in the brain is strong enough in maintaining an equilibrium in dopamine level between the basal ganglia and limbic system involves emotional circuits. This can be achieved by continuously estimating the information from the above regions and then send back the corresponding potential response and inhibitory controller to these regions by the prefrontal cortex. In the individuals with addiction, the diminutive control over behavior by the prefrontal cortex becomes weaken with the severity. Subsequently, the basal circuitry on dopamine regulation may get further impaired through noise stress exposure by trailing much of the prefrontal cortex inhibitory control on the circuits in response to stimuli

Figure 2: Normally, the prefrontal cortex in the brain is strong enough in maintaining an equilibrium in dopamine level between the basal ganglia and limbic system involves emotional circuits. This can be achieved by continuously estimating the information from the above regions and then send back the corresponding potential response and inhibitory controller to these regions by the prefrontal cortex. In the individuals with addiction, the diminutive control over behavior by the prefrontal cortex becomes weaken with the severity. Subsequently, the basal circuitry on dopamine regulation may get further impaired through noise stress exposure by trailing much of the prefrontal cortex inhibitory control on the circuits in response to stimuli