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Cover page of the Journal of Health Sciences
REVIEW ARTICLE
Year : 2020  |  Volume : 13  |  Issue : 1  |  Page : 5-10

Rickettsial disease existence in India: resurgence in outbreaks with the advent of 20th century


Department of Microbiology, G B Pant Institute of Postgraduate Medical Education and Research, New Delhi, India

Correspondence Address:
Dr. Abha Sharma
G B Pant Institute of Postgraduate Medical Education and Research, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/kleuhsj.kleuhsj_162_19

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Rickettsial infections are both one of the oldest and recently recognized reemerging zoonotic infections. Misdiagnosis and underreporting of rickettsial infections are significant public health problems leading to extensive investigations in patients with fever of unknown origin, thus contributing to economic burden on families. We review the situation of rickettsial outbreaks in India with the advent of the 20th century. We did a PubMed and Google search for literature available for rickettsial outbreaks in India. Literature was searched for outbreaks that were reported before the year 2000 and after the year 2000. The data were compiled and tabulated for comparative and descriptive analysis of the clinicoepidemiological profile, diagnosis, and existence of rickettsial infections in India. Rickettsial infections are reemerging and are reported from almost all parts of India such as Himachal Pradesh, Rajasthan, Jammu and Kashmir, Uttaranchal, Maharashtra, Tamil Nadu, Karnataka, Kerala, Assam, Mizoram, and West Bengal. Nonspecific clinical presentation and nonavailability of sensitive and specific diagnostic test make it difficult to document the diagnosis of these infections in India. Recently, molecular biological methods such as polymerase chain reaction and loop-mediated isothermal amplification have been developed but available only at reference laboratories.


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