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Cover page of the Journal of Health Sciences
ORIGINAL ARTICLE
Year : 2014  |  Volume : 7  |  Issue : 1  |  Page : 12-14

Effect of Amavatavidhvansa rasa: A herbo-mineral formulation on carrageenan - Induced inflammation in rats


1 K.L.E. University's College of Pharmacy, Belgaum, Karnataka, India
2 Department of Pharmacognosy, K.L.E. University's College of Pharmacy; Dr. Prabhakar Kore Basic Science Research Centre, K.L.E University, Belgaum, Karnataka, India

Correspondence Address:
Sunil S Jalalpure
Department of Pharmacognosy, K.L.E. University's College of Pharmacy, Belgaum, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2349-5006.135027

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Objective: To evaluate the anti-inflammatory activity of Amavatavidhvansa rasa (AVVR) using Wister albino rats. Materials and Methods: Roots of P. zeylanica L. were collected from local area of Belgaum, Karnataka. A. ferox L. was collected from Varanasi, Uttar Pradesh. Mercury and sulfur (Merck Lab, Mumbai) carrageenan (Sigma, USA) were of pharmaceutical grade. Amavatavidhvansa rasa formulation was prepared as per classical formula mentioned in Bhaishyaja Kalpana.Carrageenan was used to induce inflammation in rat. Results: The anti-inflammatory activity of AVVR against carrageenan-induced paw edema shows that all the three doses have significant effect and markedly reduced the swelling of paw. Conclusion: AVVR exerts a significant protective effect against carrageenan-induced paw edema in rats.


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